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“Crystal Former is very easy to set up and handle during follow-up visual inspection. It offers unique capabilities of gradient screening.  It speeds up the whole process of crystallization. For some projects it helps us identify novel crystallization hits.”

Dr Nickolay Chirgadze
University Health Network, Toronto

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ICCBM 13
September 12-16th, 2010
Dublin, Ireland
 
PSDI Meeting
November 14-17th, 2010
Oxford, UK


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Terese Bergfors: 
“We use the Crystal
Former as part of our
overall crystallization
strategy..."
 


 
  Products
XZ Dialysis System
Description: 

Dialysis protein crystallization is a well-established method for protein crystallization developed during the early days of structural biology. Dialysis is the only technique that allows crystallization of a biological macromolecule by either salting in or salting out. Although it is a proven crystallization method, that has been used to crystallize and solve the structure of hundreds of proteins (examples listed below), it has been labor intensive and required significant amounts of protein.
 
The disposable XZ™ microfluidic dialysis technology has been developed to specifically address these issues. With the XZ™ microfluidic dialysis technology, dialysis protein crystallization trials as low as 15nL/reaction can be easily and quickly setup. This reaction volume represents a reduction in protein consumption per experiment that is > 3,000 times lower than the currently available dialysis products. Another major advantage of the XZ™ plates is its high-throughput compatibility with common liquid dispensing and imaging systems. In addition, the XZ™ microfluidic dialysis technology offers a clear path to structure due to straight forward scale-up designs, easy loop access for crystal harvesting, and in-situ x-ray diffraction capability.

For more information about the XZ System please see XZ Dialysis System

For User Manual of the XZ Dialysis System please click here

Watch the XZ system in action please click here

 
Name
XZ Starter Kit


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